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Adaptive design of mRNA-loaded extracellular vesicles for targeted immunotherapy of cancer

The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains challenging. Here, we show an adaptive strategy that enable...

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Detalles Bibliográficos
Autores principales: Dong, Shiyan, Liu, Xuan, Bi, Ye, Wang, Yifan, Antony, Abin, Lee, DaeYong, Huntoon, Kristin, Jeong, Seongdong, Ma, Yifan, Li, Xuefeng, Deng, Weiye, Schrank, Benjamin R., Grippin, Adam J., Ha, JongHoon, Kang, Minjeong, Chang, Mengyu, Zhao, Yarong, Sun, Rongze, Sun, Xiangshi, Yang, Jie, Chen, Jiayi, Tang, Sarah K., Lee, L. James, Lee, Andrew S., Teng, Lirong, Wang, Shengnian, Teng, Lesheng, Kim, Betty Y. S., Yang, Zhaogang, Jiang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587228/
https://www.ncbi.nlm.nih.gov/pubmed/37857647
http://dx.doi.org/10.1038/s41467-023-42365-5