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TEAD4 antagonizes cellular senescence by remodeling chromatin accessibility at enhancer regions

Dramatic alterations in epigenetic landscapes are known to impact genome accessibility and transcription. Extensive evidence demonstrates that senescent cells undergo significant changes in chromatin structure; however, the mechanisms underlying the crosstalk between epigenetic parameters and gene e...

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Detalles Bibliográficos
Autores principales: Zhang, Donghui, Zhu, Yanmei, Ju, Yanmin, Zhang, Hongyong, Zou, Xiaopeng, She, Shangrong, Zhu, Danping, Guan, Yiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587282/
https://www.ncbi.nlm.nih.gov/pubmed/37856006
http://dx.doi.org/10.1007/s00018-023-04980-9