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TEAD4 antagonizes cellular senescence by remodeling chromatin accessibility at enhancer regions
Dramatic alterations in epigenetic landscapes are known to impact genome accessibility and transcription. Extensive evidence demonstrates that senescent cells undergo significant changes in chromatin structure; however, the mechanisms underlying the crosstalk between epigenetic parameters and gene e...
Autores principales: | Zhang, Donghui, Zhu, Yanmei, Ju, Yanmin, Zhang, Hongyong, Zou, Xiaopeng, She, Shangrong, Zhu, Danping, Guan, Yiting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587282/ https://www.ncbi.nlm.nih.gov/pubmed/37856006 http://dx.doi.org/10.1007/s00018-023-04980-9 |
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