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Treatment of stroke in aged male and female rats with Vepoloxamer and tPA reduces neurovascular damage

Stroke is a leading cause of death and disability worldwide, mainly affecting the elderly. Unfortunately, current treatments for acute ischemic stroke warrant improvement. To date, tissue plasminogen activator (tPA) is of limited use in stroke patients mainly due to its narrow therapeutic window and...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Luo, Hao, Li, Chao, Teng, Hua, Powell, Brianna, Lu, Mei, Chopp, Michael, Zhang, Zheng Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587547/
https://www.ncbi.nlm.nih.gov/pubmed/37869138
http://dx.doi.org/10.3389/fneur.2023.1282736