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Prioritization of risk genes for Alzheimer’s disease: an analysis framework using spatial and temporal gene expression data in the human brain based on support vector machine

Background: Alzheimer’s disease (AD) is a complex disorder, and its risk is influenced by multiple genetic and environmental factors. In this study, an AD risk gene prediction framework based on spatial and temporal features of gene expression data (STGE) was proposed. Methods: We proposed an AD ris...

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Detalles Bibliográficos
Autores principales: Wang, Shiyu, Fang, Xixian, Wen, Xiang, Yang, Congying, Yang, Ying, Zhang, Tianxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587557/
https://www.ncbi.nlm.nih.gov/pubmed/37867597
http://dx.doi.org/10.3389/fgene.2023.1190863