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Breast cancer risk prediction using Tyrer-Cuzick algorithm with an 18-SNPs polygenic risk score in a European population with below-average breast cancer incidence

GOALS: To determine whether an 18 single nucleotide polymorphisms (SNPs) polygenic risk score (PRS18) improves breast cancer (BC) risk prediction for women at above-average risk of BC, aged 40–49, in a Central European population with BC incidence below EU average. METHODS: 502 women aged 40–49 year...

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Detalles Bibliográficos
Autores principales: Oblak, Tjaša, Škerl, Petra, Narang, Benjamin J., Blagus, Rok, Krajc, Mateja, Novaković, Srdjan, Žgajnar, Janez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587756/
https://www.ncbi.nlm.nih.gov/pubmed/37857130
http://dx.doi.org/10.1016/j.breast.2023.103590