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Breast cancer risk prediction using Tyrer-Cuzick algorithm with an 18-SNPs polygenic risk score in a European population with below-average breast cancer incidence
GOALS: To determine whether an 18 single nucleotide polymorphisms (SNPs) polygenic risk score (PRS18) improves breast cancer (BC) risk prediction for women at above-average risk of BC, aged 40–49, in a Central European population with BC incidence below EU average. METHODS: 502 women aged 40–49 year...
Autores principales: | Oblak, Tjaša, Škerl, Petra, Narang, Benjamin J., Blagus, Rok, Krajc, Mateja, Novaković, Srdjan, Žgajnar, Janez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587756/ https://www.ncbi.nlm.nih.gov/pubmed/37857130 http://dx.doi.org/10.1016/j.breast.2023.103590 |
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