Prunetin in a GPR30-dependent manner mitigates renal ischemia/reperfusion injury in rats via interrupting indoxyl sulfate/TLR4/TRIF, RIPK1/RIPK3/MLKL, and RIPK3/PGAM5/DRP-1 crosstalk

The potential health benefits of phytochemicals in preventing and treating diseases have gained increasing attention. Here, we proved that the methylated isoflavone prunetin possesses a reno-therapeutic effect against renal ischemia/reperfusion (I/R) insult by activating G protein-coupled receptor 3...

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Detalles Bibliográficos
Autores principales: Hamed, Ahmed B., El-Abhar, Hanan S., Abdallah, Dalaal M., Ahmed, Kawkab A., Abulfadl, Yasmin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587762/
https://www.ncbi.nlm.nih.gov/pubmed/37868646
http://dx.doi.org/10.1016/j.jsps.2023.101818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587762/
https://www.ncbi.nlm.nih.gov/pubmed/37868646
http://dx.doi.org/10.1016/j.jsps.2023.101818

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