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HMGB1 Release Induced by EV71 Infection Exacerbates Blood-Brain Barrier Disruption via VE-cadherin Phosphorylation

PURPOSE: EV71 (Enterovirus 71) is a major causative agent of the outbreaks of HFMD (hand, foot, and mouth disease), which is associated with neurological damage caused by permeability disruption of BBB (blood-brain barrier). HMGB1 (high-mobility group box 1) is a widely expressed nuclear protein tha...

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Detalles Bibliográficos
Autores principales: You, Qiao, Wu, Jing, Liu, Ye, Zhang, Fang, Jiang, Na, Tian, Xiaoyan, Cai, Yurong, Yang, Enhui, Lyu, Ruining, Zheng, Nan, Chen, Deyan, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587765/
https://www.ncbi.nlm.nih.gov/pubmed/37832655
http://dx.doi.org/10.1016/j.virusres.2023.199240