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Arginase2 mediates contrast-induced acute kidney injury via facilitating nitrosative stress in tubular cells

Contrast-induced acute kidney injury(CI-AKI) is the third cause of AKI. Although tubular injury has been regarded as an important pathophysiology of CI-AKI, the underlying mechanism remains elusive. Here, we found arginase2(ARG2) accumulated in the tubules of CI-AKI mice, and was upregulated in iohe...

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Detalles Bibliográficos
Autores principales: Zhou, Ling-yun, Liu, Kun, Yin, Wen-jun, Xie, Yue-liang, Wang, Jiang-lin, Zuo, Shan-ru, Tang, Zhi-yao, Wu, Yi-feng, Zuo, Xiao-cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587771/
https://www.ncbi.nlm.nih.gov/pubmed/37856999
http://dx.doi.org/10.1016/j.redox.2023.102929