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Solid-Phase Collateral Cleavage System Based on CRISPR/Cas12 and Its Application toward Facile One-Pot Multiplex Double-Stranded DNA Detection

[Image: see text] The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 12 (Cas12) system is attracting interest for its potential as a next-generation nucleic acid detection tool. The system can recognize double-stranded DNA (dsDNA) based on Cas12-CRISPR RN...

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Detalles Bibliográficos
Autores principales: Shigemori, Hiroki, Fujita, Satoshi, Tamiya, Eiichi, Wakida, Shin-ichi, Nagai, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587867/
https://www.ncbi.nlm.nih.gov/pubmed/37782626
http://dx.doi.org/10.1021/acs.bioconjchem.3c00294