Chemosensitivity to doxorubicin in primary cells derived from tumor of FVB/N-Trp53(tm1Hw1) with TALEN-mediated Trp53 mutant gene

BACKGROUND: To evaluate the chemosensitivity to doxorubicin (DOX) in two primary cells derived from a tumor of FVB/N-Trp53(tm1Hw1) knockout (KO) mice with TALEN-mediated Trp53 mutant gene, we evaluated the cell survivability, cell cycle distribution, apoptotic cell numbers and apoptotic protein expr...

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Detalles Bibliográficos
Autores principales: Yun, Woobin, Kim, Ji Eun, Jin, You Jeong, Roh, Yu Jeong, Song, Hee Jin, Seol, Ayun, Kim, Tae Ryeol, Min, Kyeong Seon, Park, Eun Seo, Park, Gi Ho, Kang, Hyun Gu, Choi, Yeon Shik, Hwang, Dae Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588074/
https://www.ncbi.nlm.nih.gov/pubmed/37864254
http://dx.doi.org/10.1186/s42826-023-00175-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588074/
https://www.ncbi.nlm.nih.gov/pubmed/37864254
http://dx.doi.org/10.1186/s42826-023-00175-2

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