ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer

BACKGROUND: Tumor cells can resist chemotherapy-induced pyroptosis through glycolytic reprogramming. Estrogen-related receptor alpha (ERRα) is a central regulator of cellular energy metabolism associated with poor cancer prognosis. Herein, we refine the oncogenic role of ERRα in the pyroptosis pathw...

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Detalles Bibliográficos
Autores principales: Su, Pingping, Mao, Xiaodan, Ma, Jincheng, Huang, Lixiang, Yu, Lirui, Tang, Shuting, Zhuang, Mingzhi, Lu, Zhonglei, Osafo, Kelvin Stefan, Ren, Yuan, Wang, Xinrui, Lin, Xite, Huang, Leyi, Huang, Xiaoli, Braicu, Elena Ioana, Sehouli, Jalid, Sun, Pengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588109/
https://www.ncbi.nlm.nih.gov/pubmed/37864196
http://dx.doi.org/10.1186/s13046-023-02834-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588109/
https://www.ncbi.nlm.nih.gov/pubmed/37864196
http://dx.doi.org/10.1186/s13046-023-02834-7

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