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NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration
BACKGROUND: Neovascular age-related macular degeneration causes vision loss from destructive angiogenesis, termed choroidal neovascularization (CNV). Cx3cr1(−/−) mice display alterations in non-classical monocytes and microglia with increased CNV size, suggesting that non-classical monocytes may inh...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588116/ https://www.ncbi.nlm.nih.gov/pubmed/37858232 http://dx.doi.org/10.1186/s12974-023-02928-1 |