Cross-tissue patterns of DNA hypomethylation reveal genetically distinct histories of cell development

BACKGROUND: Establishment of DNA methylation (DNAme) patterns is essential for balanced multi-lineage cellular differentiation, but exactly how these patterns drive cellular phenotypes is unclear. While > 80% of CpG sites are stably methylated, tens of thousands of discrete CpG loci form hypometh...

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Detalles Bibliográficos
Autores principales: Scott, Timothy J., Hansen, Tyler J., McArthur, Evonne, Hodges, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588161/
https://www.ncbi.nlm.nih.gov/pubmed/37858046
http://dx.doi.org/10.1186/s12864-023-09622-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588161/
https://www.ncbi.nlm.nih.gov/pubmed/37858046
http://dx.doi.org/10.1186/s12864-023-09622-9

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