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Cross-tissue patterns of DNA hypomethylation reveal genetically distinct histories of cell development
BACKGROUND: Establishment of DNA methylation (DNAme) patterns is essential for balanced multi-lineage cellular differentiation, but exactly how these patterns drive cellular phenotypes is unclear. While > 80% of CpG sites are stably methylated, tens of thousands of discrete CpG loci form hypometh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588161/ https://www.ncbi.nlm.nih.gov/pubmed/37858046 http://dx.doi.org/10.1186/s12864-023-09622-9 |