Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease

BACKGROUND: Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. Impaired autophagy in plaque-associated microglia (PAM) has been reported to accelerate amyloid plaque deposition and cognitive impairment in AD pathogenesis. Recent evidence suggests that the transcription f...

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Detalles Bibliográficos
Autores principales: Wang, Xueting, Xie, Yuqi, Chen, Guijuan, Lu, Yapeng, Wang, Dan, Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588168/
https://www.ncbi.nlm.nih.gov/pubmed/37864249
http://dx.doi.org/10.1186/s12974-023-02931-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588168/
https://www.ncbi.nlm.nih.gov/pubmed/37864249
http://dx.doi.org/10.1186/s12974-023-02931-6

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