Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition

BACKGROUND: To support proliferation and survival within a challenging microenvironment, cancer cells must reprogramme their metabolism. As such, targeting cancer cell metabolism is a promising therapeutic avenue. However, identifying tractable nodes of metabolic vulnerability in cancer cells is cha...

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Detalles Bibliográficos
Autores principales: Holt, Amy K., Najumudeen, Arafath K., Collard, Tracey J., Li, Hao, Millett, Laura M., Hoskin, Ashley J., Legge, Danny N., Mortensson, Eleanor M. H., Flanagan, Dustin J., Jones, Nicholas, Kollareddy, Madhu, Timms, Penny, Hitchings, Matthew D., Cronin, James, Sansom, Owen J., Williams, Ann C., Vincent, Emma E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588174/
https://www.ncbi.nlm.nih.gov/pubmed/37858256
http://dx.doi.org/10.1186/s40170-023-00318-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588174/
https://www.ncbi.nlm.nih.gov/pubmed/37858256
http://dx.doi.org/10.1186/s40170-023-00318-y

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