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Accurate interpretation of p53 immunohistochemical patterns is a surrogate biomarker for TP53 alterations in large B-cell lymphoma

BACKGROUND: To clarify the relationship between p53 immunohistochemistry (IHC) staining and TP53 alterations (including mutations and deletions) in large B-cell lymphomas (LBCLs) and to explore the possibility of p53 IHC expression patterns as surrogate markers for TP53 alterations. METHODS: A total...

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Detalles Bibliográficos
Autores principales: Li, Xinyi, Luo, Danju, Zhang, Liling, Li, Qiuhui, Fan, Jun, Zhang, Jiwei, Huang, Bo, Yang, Ming, Nie, Xiu, Chang, Xiaona, Pan, Huaxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588220/
https://www.ncbi.nlm.nih.gov/pubmed/37858047
http://dx.doi.org/10.1186/s12885-023-11513-x