Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging

BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) technologies enable the capture of gene expression heterogeneity and consequently facilitate the study of cell-to-cell variability at the cell type level. Although different methods have been proposed to quantify cell-to-cell variability, it is uncl...

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Detalles Bibliográficos
Autores principales: Zheng, Huiwen, Vijg, Jan, Fard, Atefeh Taherian, Mar, Jessica Cara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588274/
https://www.ncbi.nlm.nih.gov/pubmed/37864221
http://dx.doi.org/10.1186/s13059-023-03036-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588274/
https://www.ncbi.nlm.nih.gov/pubmed/37864221
http://dx.doi.org/10.1186/s13059-023-03036-2

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