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Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging
BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) technologies enable the capture of gene expression heterogeneity and consequently facilitate the study of cell-to-cell variability at the cell type level. Although different methods have been proposed to quantify cell-to-cell variability, it is uncl...
Autores principales: | Zheng, Huiwen, Vijg, Jan, Fard, Atefeh Taherian, Mar, Jessica Cara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588274/ https://www.ncbi.nlm.nih.gov/pubmed/37864221 http://dx.doi.org/10.1186/s13059-023-03036-2 |
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