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Roxadustat promotes hypoxia‐inducible factor‐1α/vascular endothelial growth factor signalling to enhance random skin flap survival in rats

Random skin flaps have limited clinical application as a broad surgical reconstruction treatment because of distal necrosis. The prolyl hydroxylase domain‐containing protein inhibitor roxadustat (RXD) enhances angiogenesis and reduces oxidative stress and inflammation. This study explored the functi...

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Detalles Bibliográficos
Autores principales: Lan, Qicheng, Wang, Kaitao, Meng, Zhefeng, Lin, Hang, Zhou, Taotao, Lin, Yi, Jiang, Zhikai, Chen, Jianpeng, Liu, Xuao, Lin, Yuting, Lin, Dingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588316/
https://www.ncbi.nlm.nih.gov/pubmed/37225176
http://dx.doi.org/10.1111/iwj.14235