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Gene therapy for diabetic foot ulcers: Interim analysis of a randomised, placebo‐controlled phase 3 study of VM202 (ENGENSIS), a plasmid DNA expressing two isoforms of human hepatocyte growth factor

To evaluate the status of a 7‐month phase 3 study conducted to test the effect of intramuscular injections of VM202 (ENGENSIS), a plasmid DNA encoding human hepatocyte growth factor, into the calf muscles of chronic nonhealing diabetic foot ulcers with concomitant peripheral artery disease. The phas...

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Detalles Bibliográficos
Autores principales: Perin, Emerson, Loveland, Lacey, Caporusso, Joseph, Dove, Cyaandi, Motley, Travis, Sigal, Felix, Vartivarian, Mher, Oliva, Francisco, Armstrong, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588355/
https://www.ncbi.nlm.nih.gov/pubmed/37230802
http://dx.doi.org/10.1111/iwj.14226