14‐3‐3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C‐terminal helices

Ca(2+)/CaM‐dependent protein kinase kinases 1 and 2 (CaMKK1 and CaMKK2) phosphorylate and enhance the catalytic activity of downstream kinases CaMKI, CaMKIV, and protein kinase B. Accordingly, CaMKK1 and CaMKK2 regulate key physiological and pathological processes, such as tumorigenesis, neuronal mo...

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Detalles Bibliográficos
Autores principales: Petrvalska, Olivia, Honzejkova, Karolina, Koupilova, Nicola, Herman, Petr, Obsilova, Veronika, Obsil, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588359/
https://www.ncbi.nlm.nih.gov/pubmed/37817008
http://dx.doi.org/10.1002/pro.4805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588359/
https://www.ncbi.nlm.nih.gov/pubmed/37817008
http://dx.doi.org/10.1002/pro.4805

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