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14‐3‐3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C‐terminal helices
Ca(2+)/CaM‐dependent protein kinase kinases 1 and 2 (CaMKK1 and CaMKK2) phosphorylate and enhance the catalytic activity of downstream kinases CaMKI, CaMKIV, and protein kinase B. Accordingly, CaMKK1 and CaMKK2 regulate key physiological and pathological processes, such as tumorigenesis, neuronal mo...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588359/ https://www.ncbi.nlm.nih.gov/pubmed/37817008 http://dx.doi.org/10.1002/pro.4805 |