Oral Administration of Glucosylceramide Suppresses Tumor Growth by Affecting the Ceramide/Sphingosine-1-Phosphate Balance in Breast Cancer Tissue

BACKGROUND: Ceramide and sphingosine-1-phosphate (S1P) play opposing roles in cell death and survival, and maintain a dynamic balance called the sphingolipid rheostat. Glucosylceramide is a substrate to generate ceramide but its effect on breast cancer by oral administration was never tested. The pu...

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Detalles Bibliográficos
Autores principales: Moro, Kazuki, Ichikawa, Hiroshi, Koyama, Yu, Abe, Shun, Uchida, Haruka, Naruse, Kana, Obata, Yasuo, Tsuchida, Junko, Toshikawa, Chie, Ikarashi, Mayuko, Muneoka, Yusuke, Miura, Kohei, Tajima, Yosuke, Shimada, Yoshifumi, Kobayashi, Takashi, Sakata, Jun, Takabe, Kazuaki, Wakai, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588502/
https://www.ncbi.nlm.nih.gov/pubmed/37869237
http://dx.doi.org/10.14740/wjon1656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588502/
https://www.ncbi.nlm.nih.gov/pubmed/37869237
http://dx.doi.org/10.14740/wjon1656

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