The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes

The hyperexpression of human leukocyte antigen class I (HLA-I) molecules on pancreatic beta-cells is widely accepted as a hallmark feature of type 1 diabetes pathogenesis. This response is important clinically since it may increase the visibility of beta-cells to autoreactive CD8+ T-cells, thereby a...

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Detalles Bibliográficos
Autores principales: Russell, Mark A., Richardson, Sarah J., Morgan, Noel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588626/
https://www.ncbi.nlm.nih.gov/pubmed/37867531
http://dx.doi.org/10.3389/fendo.2023.1270325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588626/
https://www.ncbi.nlm.nih.gov/pubmed/37867531
http://dx.doi.org/10.3389/fendo.2023.1270325

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