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The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes
The hyperexpression of human leukocyte antigen class I (HLA-I) molecules on pancreatic beta-cells is widely accepted as a hallmark feature of type 1 diabetes pathogenesis. This response is important clinically since it may increase the visibility of beta-cells to autoreactive CD8+ T-cells, thereby a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588626/ https://www.ncbi.nlm.nih.gov/pubmed/37867531 http://dx.doi.org/10.3389/fendo.2023.1270325 |