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Multiple endocrine neoplasia type 1 with Zollinger–Ellison syndrome: clinicopathological analysis of a Japanese family with focus on menin immunohistochemistry

BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by the occurrence of multiple epithelial neuroendocrine tumors (NETs) and non-NETs in various organs. MEN1 encodes a 610-amino acid-long tumor suppressor protein, menin. The optimal treatment for m...

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Detalles Bibliográficos
Autores principales: Kimura, Noriko, Hirata, Yasuji, Iwashiro, Nozomu, Kijima, Hiroshi, Takayasu, Shinobu, Yamagata, Satoshi, Sakihara, Satoru, Uchino, Shinya, Ohara, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588651/
https://www.ncbi.nlm.nih.gov/pubmed/37867522
http://dx.doi.org/10.3389/fendo.2023.1221514