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Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation

Introduction: We aimed to demonstrate non-invasive measurements of regional oxygen extraction fraction (OEF) from quantitative BOLD MRI modeling at baseline and after pharmacological vasodilation. We hypothesized that OEF decreases in response to vasodilation with acetazolamide (ACZ) in healthy cond...

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Detalles Bibliográficos
Autores principales: Le, Linh N. N., Wheeler, Gregory J., Holy, Emily N., Donnay, Corinne A., Blockley, Nicholas P., Yee, Alan H., Ng, Kwan L., Fan, Audrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588655/
https://www.ncbi.nlm.nih.gov/pubmed/37869717
http://dx.doi.org/10.3389/fphys.2023.1231793