A pilot study: effect of irisin on trabecular bone in a streptozotocin-induced animal model of type 1 diabetic osteopathy utilizing a micro-CT

BACKGROUND: Osteoporosis is a significant co-morbidity of type 1 diabetes mellitus (DM1) leading to increased fracture risk. Exercise-induced hormone ‘irisin’ in low dosage has been shown to have a beneficial effect on bone metabolism by increasing osteoblast differentiation and reducing osteoclast...

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Detalles Bibliográficos
Autores principales: Mohsin, Sahar, Brock, Fiona, Kaimala, Suneesh, Greenwood, Charlene, Sulaiman, Mohsin, Rogers, Keith, Adeghate, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Diabetes and Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588705/
https://www.ncbi.nlm.nih.gov/pubmed/37868046
http://dx.doi.org/10.7717/peerj.16278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588705/
https://www.ncbi.nlm.nih.gov/pubmed/37868046
http://dx.doi.org/10.7717/peerj.16278

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