Global and tissue-specific aging effects on murine proteomes

Maintenance of protein homeostasis degrades with age, contributing to aging-related decline and disease. Previous studies have primarily surveyed transcriptional aging changes. To define the effects of age directly at the protein level, we perform discovery-based proteomics in 10 tissues from 20 C57...

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Detalles Bibliográficos
Autores principales: Keele, Gregory R., Zhang, Ji-Gang, Szpyt, John, Korstanje, Ron, Gygi, Steven P., Churchill, Gary A., Schweppe, Devin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588767/
https://www.ncbi.nlm.nih.gov/pubmed/37405913
http://dx.doi.org/10.1016/j.celrep.2023.112715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588767/
https://www.ncbi.nlm.nih.gov/pubmed/37405913
http://dx.doi.org/10.1016/j.celrep.2023.112715

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