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Microglial WNT5A supports dendritic spines maturation and neuronal firing
There is increasing evidence showing that microglia play a critical role in mediating synapse formation and spine growth, although the molecular mechanism remains elusive. Here, we demonstrate that the secreted morphogen WNT family member 5A (WNT5A) is the most abundant WNT expressed in microglia an...
Autores principales: | Yeh, Hana, Woodbury, Maya E., Ingraham Dixie, Kaitlin L., Ikezu, Tsuneya, Ikezu, Seiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588768/ https://www.ncbi.nlm.nih.gov/pubmed/36395958 http://dx.doi.org/10.1016/j.bbi.2022.11.003 |
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