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Transepithelial Barrier Dysfunction Drives Microbiota Dysbiosis to Initiate Epithelial Clock-driven Inflammation
BACKGROUND: Factors that contribute to inflammatory bowel disease [IBD] pathogenesis include genetic polymorphisms, barrier loss, and microbial dysbiosis. A major knowledge gap exists in the origins of the colitogenic microbiome and its relationship with barrier impairment. Epithelial myosin light c...
Autores principales: | Pai, Yu-Chen, Li, Yi-Hsuan, Turner, Jerrold R, Yu, Linda Chia-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588795/ https://www.ncbi.nlm.nih.gov/pubmed/37004200 http://dx.doi.org/10.1093/ecco-jcc/jjad064 |
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