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Discovery of Novel α-Aminophosphonates with Hydrazone as Potential Antiviral Agents Combined With Active Fragment and Molecular Docking

A series of novel α-aminophosphonate derivatives containing hydrazone were designed and synthesized based on active fragments. Bioassay results demonstrated that title compounds possessed good activities against tobacco mosaic virus. Among them, compounds 6a, 6g, 6i, and 6j were equivalent to the co...

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Detalles Bibliográficos
Autores principales: Tian, Jia, Ji, Renjing, Wang, Huan, Li, Siyu, Zhang, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588822/
https://www.ncbi.nlm.nih.gov/pubmed/37868694
http://dx.doi.org/10.3389/fchem.2022.911453