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Tunable hydrogel viscoelasticity modulates human neural maturation

Human-induced pluripotent stem cells (hiPSCs) have emerged as a promising in vitro model system for studying neurodevelopment. However, current models remain limited in their ability to incorporate tunable biomechanical signaling cues imparted by the extracellular matrix (ECM). The native brain ECM...

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Detalles Bibliográficos
Autores principales: Roth, Julien G., Huang, Michelle S., Navarro, Renato S., Akram, Jason T., LeSavage, Bauer L., Heilshorn, Sarah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588948/
https://www.ncbi.nlm.nih.gov/pubmed/37862423
http://dx.doi.org/10.1126/sciadv.adh8313