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C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy

The overall oocyte quality declines with aging, and this effect is strongly associated with a higher reactive oxygen species (ROS) level and the resultant oxidative damage. C-type natriuretic peptide (CNP) is a well-characterized physiological meiotic inhibitor that has been successfully used to imp...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Li, Chan, Liu, Qingyang, Li, Jingmei, Wu, Hao, Xu, Rui, Sun, Yidan, Cheng, Ming, Zhao, Xiaoe, Pan, Menghao, Wei, Qiang, Ma, Baohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588981/
https://www.ncbi.nlm.nih.gov/pubmed/37860954
http://dx.doi.org/10.7554/eLife.88523