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YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions

Maladaptive repair of acute kidney injury (AKI) is associated with a high risk of developing chronic kidney disease deemed irremediable even in present days. When AKI arises from ischemia-reperfusion injury, hypoxia usually plays a major role. Although both hypoxia-inducible factor-1α (HIF-1α) and y...

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Detalles Bibliográficos
Autores principales: Chang, Heng-Ai, Ou Yang, Rui-Zhi, Su, Jing-Ming, Nguyen, Thi My Hang, Sung, Junne-Ming, Tang, Ming-Jer, Chiu, Wen-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589224/
https://www.ncbi.nlm.nih.gov/pubmed/37863897
http://dx.doi.org/10.1038/s41420-023-01687-5