Identification of novel pathogenic roles of BLZF1/ATF6 in tumorigenesis of gastrointestinal stromal tumor showing Golgi-localized mutant KIT

Gastrointestinal stromal tumors (GISTs) frequently show KIT mutations, accompanied by overexpression and aberrant localization of mutant KIT (MT-KIT). As previously established by multiple studies, including ours, we confirmed that MT-KIT initiates downstream signaling in the Golgi complex. Basic le...

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Detalles Bibliográficos
Autores principales: Kwon, Yujin, Kim, Jiyoon, Cho, Su-Yeon, Kang, Yoon Jin, Lee, Jongsoo, Kwon, Jaeyoung, Rhee, Hyungjin, Bauer, Sebastian, Kim, Hyung-Sik, Lee, Esak, Kim, Han Sang, Jung, Jae Hung, Kim, Hoguen, Kim, Won Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589262/
https://www.ncbi.nlm.nih.gov/pubmed/37704840
http://dx.doi.org/10.1038/s41418-023-01220-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589262/
https://www.ncbi.nlm.nih.gov/pubmed/37704840
http://dx.doi.org/10.1038/s41418-023-01220-2

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