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Identification of novel pathogenic roles of BLZF1/ATF6 in tumorigenesis of gastrointestinal stromal tumor showing Golgi-localized mutant KIT
Gastrointestinal stromal tumors (GISTs) frequently show KIT mutations, accompanied by overexpression and aberrant localization of mutant KIT (MT-KIT). As previously established by multiple studies, including ours, we confirmed that MT-KIT initiates downstream signaling in the Golgi complex. Basic le...
Autores principales: | Kwon, Yujin, Kim, Jiyoon, Cho, Su-Yeon, Kang, Yoon Jin, Lee, Jongsoo, Kwon, Jaeyoung, Rhee, Hyungjin, Bauer, Sebastian, Kim, Hyung-Sik, Lee, Esak, Kim, Han Sang, Jung, Jae Hung, Kim, Hoguen, Kim, Won Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589262/ https://www.ncbi.nlm.nih.gov/pubmed/37704840 http://dx.doi.org/10.1038/s41418-023-01220-2 |
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