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Lactylation of METTL16 promotes cuproptosis via m(6)A-modification on FDX1 mRNA in gastric cancer

Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a potential cancer therapeutic. However, the mechanisms underlying the initiation, propagation, and ultimate execution of cuproptosis in tumors remain unknown. Here, we show that copper content is significantly e...

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Detalles Bibliográficos
Autores principales: Sun, Lianhui, Zhang, Yuan, Yang, Boyu, Sun, Sijun, Zhang, Pengshan, Luo, Zai, Feng, Tingting, Cui, Zelin, Zhu, Ting, Li, Yuming, Qiu, Zhengjun, Fan, Guangjian, Huang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589265/
https://www.ncbi.nlm.nih.gov/pubmed/37863889
http://dx.doi.org/10.1038/s41467-023-42025-8