Circular single-stranded DNA as switchable vector for gene expression in mammalian cells

Synthetic gene networks in mammalian cells are currently limited to either protein-based transcription factors or RNA-based regulators. Here, we demonstrate a regulatory approach based on circular single-stranded DNA (Css DNA), which can be used as an efficient expression vector with switchable acti...

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Detalles Bibliográficos
Autores principales: Tang, Linlin, Tian, Zhijin, Cheng, Jin, Zhang, Yijing, Song, Yongxiu, Liu, Yan, Wang, Jinghao, Zhang, Pengfei, Ke, Yonggang, Simmel, Friedrich C., Song, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589306/
https://www.ncbi.nlm.nih.gov/pubmed/37863879
http://dx.doi.org/10.1038/s41467-023-42437-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589306/
https://www.ncbi.nlm.nih.gov/pubmed/37863879
http://dx.doi.org/10.1038/s41467-023-42437-6

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