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CD8(+) T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production

Whether CD8(+) T lymphocytes control human immunodeficiency virus infection by cytopathic or non-cytopathic mechanisms is not fully understood. Multiple studies highlighted non-cytopathic effects, but one hypothesis is that cytopathic effects of CD8(+) T cells occur before viral production. Here, to...

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Detalles Bibliográficos
Autores principales: Policicchio, Benjamin B., Cardozo-Ojeda, Erwing Fabian, Xu, Cuiling, Ma, Dongzhu, He, Tianyu, Raehtz, Kevin D., Sivanandham, Ranjit, Kleinman, Adam J., Perelson, Alan S., Apetrei, Cristian, Pandrea, Ivona, Ribeiro, Ruy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589330/
https://www.ncbi.nlm.nih.gov/pubmed/37863982
http://dx.doi.org/10.1038/s41467-023-42435-8