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Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision

We report the molecular basis of Aspergillus fumigatus oryzin, allergen Asp f 13, or alkaline proteinase ALP1, containing the sequence motif His–Asp–Ser of the subtilisin family, structure, and function at atomic detail. Given the resolution of the data (1.06 Å), we use fragment molecular replacemen...

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Detalles Bibliográficos
Autores principales: Pattelli, Olivia N., Diec, Dinh Dinh Ly, Guo, Wanting, Russi, Silvia, Fernandez, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589352/
https://www.ncbi.nlm.nih.gov/pubmed/37864071
http://dx.doi.org/10.1038/s41598-023-45028-z