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In silico design and cell-based evaluation of two dual anti breast cancer compounds targeting Bcl-2 and GPER

According to WHO statistics, breast cancer (BC) disease represents about 2.3 million diagnosed and 685,000 deaths globally. Regarding histological classification of BC, the Estrogen (ER) and Progesterone (PR) receptors negative-expression cancer, named Triple-Negative BC (TNBC), represents the most...

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Detalles Bibliográficos
Autores principales: Morelos-Garnica, Loreley-A., Guzmán-Velázquez, Sonia, Padilla-Martínez, Itzia-I., García-Sánchez, José-R., Bello, Martiniano, Bakalara, Norbert, Méndez-Luna, David, Correa-Basurto, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589355/
https://www.ncbi.nlm.nih.gov/pubmed/37863936
http://dx.doi.org/10.1038/s41598-023-43860-x