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GSDME has prognostic and immunotherapeutic significance in residual hepatocellular carcinoma after insufficient radiofrequency ablation

BACKGROUND: Heat stress can induce programmed cell death (PCD). Pyroptosis is a gasdermin-mediated PCD. This study hypothesized that insufficient radiofrequency ablation (IRFA) induced pyroptosis in hepatocellular carcinoma (HCC) and investigated its underlying mechanism and clinical significance. M...

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Detalles Bibliográficos
Autores principales: Liang, Xuexia, Liu, Qiaodan, Zhu, Shuqin, Li, Zizi, Chen, Hui, Su, Zhongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589398/
https://www.ncbi.nlm.nih.gov/pubmed/37862939
http://dx.doi.org/10.1016/j.tranon.2023.101796