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Gene expression and RNA splicing explain large proportions of the heritability for complex traits in cattle

Many quantitative trait loci (QTLs) are in non-coding regions. Therefore, QTLs are assumed to affect gene regulation. Gene expression and RNA splicing are primary steps of transcription, so DNA variants changing gene expression (eVariants) or RNA splicing (sVariants) are expected to significantly af...

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Detalles Bibliográficos
Autores principales: Xiang, Ruidong, Fang, Lingzhao, Liu, Shuli, Macleod, Iona M., Liu, Zhiqian, Breen, Edmond J., Gao, Yahui, Liu, George E., Tenesa, Albert, Mason, Brett A., Chamberlain, Amanda J., Wray, Naomi R., Goddard, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589627/
https://www.ncbi.nlm.nih.gov/pubmed/37868035
http://dx.doi.org/10.1016/j.xgen.2023.100385