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Learning functional conservation between human and pig to decipher evolutionary mechanisms underlying gene expression and complex traits

Assessment of genomic conservation between humans and pigs at the functional level can improve the potential of pigs as a human biomedical model. To address this, we developed a deep learning-based approach to learn the genomic conservation at the functional level (DeepGCF) between species by integr...

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Detalles Bibliográficos
Autores principales: Li, Jinghui, Zhao, Tianjing, Guan, Dailu, Pan, Zhangyuan, Bai, Zhonghao, Teng, Jinyan, Zhang, Zhe, Zheng, Zhili, Zeng, Jian, Zhou, Huaijun, Fang, Lingzhao, Cheng, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589632/
https://www.ncbi.nlm.nih.gov/pubmed/37868039
http://dx.doi.org/10.1016/j.xgen.2023.100390