Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells

PURPOSE: Human papilloma virus (HPV) positive head and neck squamous cell carcinoma (HNSCC) tumors respond significantly better to anticancer treatments. It is assumed to be due to a better response to radiotherapy (RT), and presumably to an increased immunogenicity. However, little is known how the...

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Detalles Bibliográficos
Autores principales: Grottker, Fridolin, Gehre, Simon, Reichardt, Clara M., Sengedorj, Azzaya, Jost, Tina, Rieckmann, Thorsten, Hecht, Markus, Gostian, Antoniu-Oreste, Frey, Benjamin, Fietkau, Rainer, Gaipl, Udo S., Rückert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589749/
https://www.ncbi.nlm.nih.gov/pubmed/37857049
http://dx.doi.org/10.1016/j.neo.2023.100944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589749/
https://www.ncbi.nlm.nih.gov/pubmed/37857049
http://dx.doi.org/10.1016/j.neo.2023.100944

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