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Allosteric crosstalk in modular proteins: Function fine-tuning and drug design

Modular proteins are regulatory proteins that carry out more than one function. These proteins upregulate or downregulate a biochemical cascade to establish homeostasis in cells. To switch the function or alter the efficiency (based on cellular needs), these proteins require different facilitators t...

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Detalles Bibliográficos
Autores principales: Abhishek, Suman, Deeksha, Waghela, Nethravathi, Krishnapura Ranganatha, Davari, Mehdi D., Rajakumara, Eerappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589753/
https://www.ncbi.nlm.nih.gov/pubmed/37867971
http://dx.doi.org/10.1016/j.csbj.2023.10.013